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Article

Investigation of loss of heterozygosity and SNP frequencies in the RET gene in papillary thyroid carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2005

Stephens L A, Powell N G, Grubb J, Jeremiah S J, Bethel J A, Demidchik E P, Bogdanova T I, Tronko M D, Thomas G A

Abstract excerpt

In both medullary carcinoma and papillary carcinoma of the thyroid, altered expression of the RET gene is implicated in tumorigenesis. Recent studies suggest that loss of heterozygosity (LOH) at the G691S SNP may be associated with tumors from patients with a history of radiation exposure. We investigated LOH for three RET SNPs (G691S, S904S, and L769L) in tumor and normal tissue from 46 patients from Ukraine and...

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Source

Identifiers

PMID: 15753666
DOI: 10.1089/thy.2005.15.100

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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