Article
p53 mutations in childhood thyroid tumours from Belarus and in thyroid tumours without radiation history.
International journal of cancer - 10 Dec 1997
Smida J, Zitzelsberger H, Kellerer A M, Lehmann L, Minkus G, Negele T, Spelsberg F, Hieber L, Demidchik E P, Lengfelder E, Bauchinger M
Abstract excerpt
Mutations in the p53 tumour-suppressor gene (exons 5-8) were investigated in 31 Belarussian childhood thyroid tumours (24 cases of papillary thyroid carcinoma, 3 benign tumours and 2 cases each of thyroiditis and goiter); 33 thyroid tumours from juveniles and adults without radiation exposures (25 carcinomas of various histological types, including 11 papillary carcinomas and 8 adenomas) and 6 tumours from adults...
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