Article
TP53 codon 72 polymorphism in radiation-associated human papillary thyroid cancer.
Oncology reports - 1 Apr 2006
Rogounovitch Tatiana I, Saenko Vladimir A, Ashizawa Kiyoto, Sedliarou Ilya A, Namba Hiroyuki, Abrosimov Aleksandr Yu, Lushnikov Eugeny F, Roumiantsev Pavel O, Konova Marina V, Petoukhova Natalia S, Tchebotareva Irina V, Ivanov Viktor K, Chekin Sergei Yu, Bogdanova Tatiana I, Tronko Mykola D, Tsyb Anatoly F, Thomas Gerry A, Yamashita Shunichi
Abstract excerpt
The study investigated an association between the germline polymorphism at TP53 codon 72 and the development of papillary thyroid cancer (PTC) following exposure to radiation from the Chernobyl accident. TP53 genotype was examined in 48 pediatric/adolescent (age at diagnosis <18 years) and 68 adult post-Chernobyl patient with PTC, 53 adult patients with sporadic PTC and 313 healthy individuals from...
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