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Article

Technical note: determination of alleles of the ovine PRNP gene using PCR-single-strand conformational polymorphism analysis.

Journal of animal science - 1 Apr 2005

Zhou H, Hickford J G H, Fang Q

Abstract excerpt

Susceptibility to scrapie in sheep is linked to variation at codons 136, 154, and 171 in the host prion protein gene (PRNP). A number of techniques are available for detecting these polymorphisms, but none allow for a rapid and accurate determination of genotype. Here we describe PCR coupled with single-strand conformational polymorphism (SSCP) analysis, which allows for the accurate identification of ovine PRNP...

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Source

Identifiers

PMID: 15753327
DOI: 10.2527/2005.834745x

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Technical note: determination of alleles of the ovine PRNP gene using PCR-single-strand conformational polymorphism analysis.PMID 15753327Read ↗

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