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Article

Fusogenic activity of EFF-1 is regulated via dynamic localization in fusing somatic cells of C. elegans.

Current biology : CB - 8 Mar 2005

del Campo Jacob J, Opoku-Serebuoh Eugene, Isaacson Ariel B, Scranton Victoria L, Tucker Morgan, Han Min, Mohler William A

Abstract excerpt

BACKGROUND: Many animal tissues form via fusion of cells. Yet in all instances of developmental cell fusion, the mechanism underlying fusion of plasma membranes remains poorly understood. EFF-1 is required for most somatic cell fusions in C. elegans, and misexpressed EFF-1 alters the normal pattern of fusing hypodermal cells. However, the autonomous activity of EFF-1, the rules governing its specificity, and the...

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PMID: 15753035
DOI: 10.1016/j.cub.2005.01.054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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