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Article

Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP.

The Biochemical journal - 1 Jul 2005

Demendi Melinda, Ishiyama Noboru, Lam Joseph S, Berghuis Albert M, Creuzenet Carole

Abstract excerpt

WbpP is the only genuine UDP-GlcNAc (UDP-N-acetylglucosamine) C4 epimerase for which both biochemical and structural data are available. This represents a golden opportunity to elucidate the molecular basis for its specificity for N-acetylated substrates. Based on the comparison of the substrate binding site of WbpP with that of other C4 epimerases that convert preferentially non-acetylated substrates, or that...

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Identifiers

PMID: 15752069
DOI: 10.1042/BJ20050263
PMCID: PMC1184549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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