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Article

Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer.

Carcinogenesis - 1 Jul 2005

Broberg Karin, Björk Jonas, Paulsson Karin, Höglund Mattias, Albin Maria

Abstract excerpt

Lack of functional telomeres can cause chromosomal aberrations. This type of genetic instability may promote tumorigenesis. We have investigated the association between mean telomere length in buccal cells (assessed with quantitative real-time PCR) and bladder cancer risk in a case-control study. Patients with bladder cancer displayed significantly shorter telomeres than control subjects (P = 0.001). Median...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15746160
DOI: 10.1093/carcin/bgi063

Genes

GSTM1
EPHX1
GSTA1
GSTP1
GSTT1
NAT1
NAT2
NQO1
XPC
XRCC1
XRCC3
XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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