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Article

Functional variants in CYP1B1, KRAS and MTHFR genes are associated with shorter telomere length in postmenopausal women.

Mechanisms of ageing and development - 1 Jul 2015

Cerne Jasmina Z, Pohar-Perme Maja, Cerkovnik Petra, Gersak Ksenija, Novakovic Srdjan

Abstract excerpt

Estrogens and antioxidants indirectly alleviate telomere attrition. However, available clinical data on the association between hormone exposure and telomere length are inconclusive. In the present study, we examined the effects of exogenous estrogen use and of some genetic factors implicated in estrogen metabolism and oxidative stress response on mean leukocyte telomere length. We studied 259 postmenopausal...

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Source

Identifiers

PMID: 25987236
DOI: 10.1016/j.mad.2015.05.003

Genes

KRAS
MTHFR
COMT
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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