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[Study on the relationship between polymorphism of insulin-receptor gene EXON2-2257 and insulin resistance in Chinese people].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Jan 2004

Wang Lu, Mi Jie, Wu Jian-xin, Zhao Xiao-yuan, Cheng Hong, Ding Xiu-yuan, Hou Dong-qing, Lu Jie, Gu Xue

Abstract excerpt

OBJECTIVE: To understand the role of insulin-receptor gene in the development of insulin resistance on a population-based study in China. METHODS: Polymerase chain reaction (PCR) was used to amplify the EXON2 of the insulin-receptor gene and all amplified products were analyzed by direct sequencing. RESULTS: Three genotypes of single nucleotide at the site of 2257 in EXON2 of the insulin-receptor gene were...

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PMID: 15061947

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