Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cumulative mutations in the genome of Echovirus 6 during establishment of a chronic infection in precursors of glial cells.

Virus genes - 1 Jan 2005

Beaulieux Frederik, Zreik Youssef, Deleage Christelle, Sauvinet Valerie, Legay Vincent, Giraudon Pascale, Kean Katherine M, Lina Bruno

Abstract excerpt

Although Enteroviruses are mainly described as responsible for acute diseases, their role in severe chronic pathology has been also established. Echovirus 6-like sequences have been detected by PCR analysis in central nervous system specimens from patients presenting with Amyotrophic Lateral Sclerosis. These findings suggested a persistent infection with viruses that underwent, genetic changes precluding viral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neuroglia

Share to Nucleic Acid Conformation

Share to Sequence Analysis

Share to Viral Plaque Assay

Share to Viral Proteins

Share to Virus Replication

Source

Identifiers

PMID: 15744568
DOI: 10.1007/s11262-004-4587-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cumulative mutations in the genome of Echovirus 6 during establishment of a chronic infection in precursors of glial cells.PMID 15744568Read ↗

Genomic variations in echovirus 30 persistent isolates recovered from a chronically infected immunodeficient child and comparison with the reference strain.Semantic proximity Read ↗

Molecular mechanisms of poliovirus persistence: key role of capsid determinants during the establishment phase.Semantic proximity Read ↗

Poliovirus internal ribosome entry segment structure alterations that specifically affect function in neuronal cells: molecular genetic analysis.Semantic proximity Read ↗

Suppression of viral RNA polymerase activity is necessary for persistent infection during the transformation of measles virus into SSPE virusSemantic proximity Read ↗

Non-AUG-Initiated Internal Translation of the L* Protein of Theiler's Virus and Importance of This Protein for Viral PersistenceSemantic proximity Read ↗

Persistent Infection of Human Oligodendrocytic and Neuroglial Cell Lines by Human Coronavirus 229ESemantic proximity Read ↗

Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytesSemantic proximity Read ↗

Characterization of Defective Viral RNA Produced during Persistent Infection of Vero Cells with Murray Valley Encephalitis VirusSemantic proximity Read ↗

Nucleotide sequences and mutations of the 5'-nontranslated region (5'NTR) of natural isolates of an epidemic echovirus 11' (prime).Semantic proximity Read ↗

Genetic adaptation to untranslated region-mediated enterovirus growth deficits by mutations in the nonstructural proteins 3AB and 3CD.Semantic proximity Read ↗

Analysis of the leader and capsid coding regions of persistent and neurovirulent strains of Theiler's virus.Semantic proximity Read ↗

Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.