Article
Analysis of the genetic diversity of the Plasmodium falciparum multidrug resistance gene 5' upstream region.
The American journal of tropical medicine and hygiene - 1 Feb 2005
Myrick Alissa, Sarr Ousmane, Dieng Therese, Ndir Omar, Mboup Souleymane, Wirth Dyann F
Abstract excerpt
Recent findings indicating a low level of polymorphism in the Plasmodium falciparum genome have led to the hypothesis that existent polymorphisms are likely to have functional significance. We tested this hypothesis by developing a map of the polymorphism in the P. falciparum multidrug resistance 1 (pfmdr1) gene 5' upstream region and assaying its correlation with drug resistance in a sample of field isolates...
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