Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar.

doi:10.1093/jac/dku125

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Article

Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar.

The Journal of antimicrobial chemotherapy - 1 Aug 2014

Gupta Bhavna, Xu Shuhui, Wang Zenglei, Sun Ling, Miao Jun, Cui Liwang, Yang Zhaoqing

Abstract excerpt

OBJECTIVES: Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) has recently emerged as an important determinant of drug resistance and mutations in the gene have been associated with several drugs. The aim of this study was to understand the level of genetic diversity in pfmrp1 and to determine the association of different mutations with altered drug susceptibilities of P. falciparum. METHODS: We...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Antimalarials
Base Sequence
Chloroquine
Drug Resistance
Ethanolamines
Fluorenes
Geography
Humans
Lumefantrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Malaria, Falciparum

Mefloquine

Multidrug Resistance-Associated Proteins

Mutation

Myanmar

Naphthyridines

Parasitic Sensitivity Tests

Plasmodium falciparum

Source

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Identifiers

PMID: 24855124
DOI: 10.1093/jac/dku125
PMCID: PMC4100709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24855124-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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