Article
HuntING4 new tumor suppressors.
Cell cycle (Georgetown, Tex.) - 1 Apr 2005
Kim Suwon
Abstract excerpt
The well-characterized function of many tumor suppressors is to directly regulate cell cycle events. We recently reported a genetic screen to identify genes that suppress loss of contact inhibition but do not inhibit normal cell proliferation. ING4, one of the genes identified by the screen, is frequently mutated in human cancer, suggesting a role for ING4 as a tumor suppressor. ING4 suppresses tumor cell...
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