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Article

The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer.

Oncogene - 14 Apr 2005

Sekine Ikuo, Sato Mitsuo, Sunaga Noriaki, Toyooka Shinichi, Peyton Michael, Parsons Ramon, Wang Weidong, Gazdar Adi F, Minna John D

Abstract excerpt

BAF180 encoding a subunit of the human SWI/SNF chromatin remodeling complex maps to 3p21, in a region where frequent allele loss has been detected in lung cancer. BAF180 can be mutated and has tumor suppressing properties in breast cancer. In addition, another member of this complex, hSNF5/INI1, is a known tumor suppressor gene (TSG) for malignant rhabdoid and childhood central nervous system tumors. Thus, BAF180...

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PMID: 15735765
DOI: 10.1038/sj.onc.1207694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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