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Article

Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.

Cancer research - 15 Mar 2008

Tessema Mathewos, Willink Randy, Do Kieu, Yu Yang Y, Yu Wayne, Machida Emi O, Brock Malcolm, Van Neste Leander, Stidley Christine A, Baylin Stephen B, Belinsky Steven A

Abstract excerpt

Chromosomal aberrations associated with lung cancer are frequently observed in the long arm of chromosome 6. A candidate susceptibility locus at 6q23-25 for lung cancer was recently identified; however, no tumor suppressor genes inactivated by mutation have been identified in this locus. Genetic, epigenetic, gene expression, and in silico screening approaches were used to select 43 genes located in 6q12-27 for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18339850
DOI: 10.1158/0008-5472.CAN-07-6325

Genes

AKAP12
TCF21
ACAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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