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Article

Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.

The Journal of biological chemistry - 13 May 2005

Enokizono Yoshiaki, Konishi Yuki, Nagata Kayoko, Ouhashi Kiyoshi, Uesugi Seiichi, Ishikawa Fuyuki, Katahira Masato

Abstract excerpt

Heterogeneous nuclear ribonucleoprotein D, also known as AUF1, has two DNA/RNA-binding domains, each of which can specifically bind to single-stranded d(TTAGGG)n, the human telomeric repeat. Here, the structure of the C-terminal-binding domain (BD2) complexed with single-stranded d(TTAGGG) determined by NMR is presented. The structure has revealed that each residue of the d(TAG) segment is recognized by BD2 in a...

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Identifiers

PMID: 15734733
DOI: 10.1074/jbc.M411822200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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