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In Vitro Properties of the Conserved Mammalian Protein hnRNP D Suggest a Role in Telomere Maintenance

1 Aug 2000

Abstract excerpt

Mammalian chromosomes terminate with a 3' tail which consists of reiterations of the G-rich repeat, d(TTAGGG). The telomeric tail is the primer for replication by telomerase, and it may also invade telomeric duplex DNA to form terminal lariat structures, or T loops. Here we show that the ubiquitous and highly conserved mammalian protein hnRNP D interacts specifically with the G-rich strand of the telomeric...

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PMID: 10891483
DOI: 10.1128/mcb.20.15.5425-5432.2000

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In Vitro Properties of the Conserved Mammalian Protein hnRNP D Suggest a Role in Telomere MaintenancePMID 10891483Read ↗

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Auto- and cross-regulation of the hnRNPs D and DLSemantic proximity Read ↗

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