Article
Genetic predisposition to latex allergy: role of interleukin 13 and interleukin 18.
Anesthesiology - 1 Mar 2005
Brown Robert H, Hamilton Robert G, Mintz Margaret, Jedlicka Anne E, Scott Alan L, Kleeberger Steven R
Abstract excerpt
BACKGROUND: Occupational exposure of healthcare workers to natural rubber latex has led to sensitization and potentially life-threatening anaphylaxis. Although environmental exposure to natural rubber latex products is necessary for sensitization, it is not sufficient. A number of genetic factors also seem to contribute to the latex sensitization; however, the multigenic nature of the allergic phenotype has made...
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