Article
Genetic predictors of inflammation in the risk of occupational asthma in young apprentices.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Jun 2013
Acouetey Dovi Stéphanie, Zmirou-Navier Denis, Avogbe Patrice Hodonou, Avogbe Patrice, Tossa Paul, Rémen Thomas, Barbaud Annick, Cornejo-Garcia José-Antonio, Blanca Miguel, Bohadana Abraham, Paris Christophe, Guéant Jean-Louis, Guéant-Rodriguez Rosa-Maria
Abstract excerpt
BACKGROUND: The influence of genetic predictors of inflammation and atopy on occupational asthma in apprentices is not known. OBJECTIVES: To assess the influence of genetic polymorphisms of IL4RA, IL13, TNFA, IL1A, and IL5 on the decline of lung function and bronchial hyperresponsiveness in a prospective follow-up study of baker/pastry maker and hairdresser apprentices. METHODS: A total of 351 apprentices were...
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