Article
Assessment of the XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro) and GSTP1 (Ile105Val) polymorphisms in the risk of cutaneous melanoma.
Journal of cancer research and clinical oncology - 1 Jul 2013
Oliveira Cristiane, Rinck-Junior José Augusto, Lourenço Gustavo Jacob, Moraes Aparecida Machado, Lima Carmen Silvia Passos
Abstract excerpt
PURPOSE: We examined the influence of XPC A2920C, XPF T30028C, TP53 Arg72Pro and GSTP1 Ile105Val polymorphisms in the risk of cutaneous melanoma (CM). METHODS: DNA from 146 CM patients and 146 controls was analysed by polymerase chain reaction (PCR)--restriction fragment length polymorphism (RFLP). RESULTS: The frequencies of XPC CC (15.1 vs. 6.9 %, P = 0.02), TP53 ArgArg (59.6 vs. 45.9 %, P = 0.02), XPC CC plus...
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