Article
XPC 939A>C and 499C>T polymorphisms and skin cancer risk: a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Ji Geng, Lin Yuan, Cao Song-Yu, Li Luo-Zhu, Chen Xin-Long, Sun Bu-Mei, Chen Chuan-Jun, Ma Hong-Xia
Abstract excerpt
The xeroderma pigmentosum complementation group C gene (XPC) has been identified as important for repairing UV-related DNA damage. Some subtle changes in this gene may impair repair efficiency and influence susceptibility to human cancers, including skin cancer. Two polymorphisms in XPC, 939A>C (rs2228001) and 499C>T (rs2228000), are considered to have possible associations with the risk of skin cancer, but the...
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