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Article

High frequency stimulation of the subthalamic nucleus is efficacious in Parkin disease.

Journal of neurology - 1 Feb 2005

Romito Luigi M A, Contarino Maria F, Ghezzi Daniele, Franzini Angelo, Garavaglia Barbara, Albanese Alberto

Abstract excerpt

High frequency stimulation (HFS) of the subthalamic nucleus (STN) is an efficacious symptomatic treatment for Parkinson's disease. We have analysed the genetic status of a series of consecutive parkinsonian patients implanted for STN HFS and compared the outcome of five carrying mutations in the parkin gene with that of the non-parkin group. All patients obtained sustained control of PD symptoms and achieved...

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Identifiers

PMID: 15729528
DOI: 10.1007/s00415-005-0638-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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