Article
Disequilibrium in distribution of resistance mutations among Mycobacterium tuberculosis Beijing and non-Beijing strains isolated from patients in Germany.
Antimicrobial agents and chemotherapy - 1 Mar 2005
Hillemann Doris, Kubica Tanja, Rüsch-Gerdes Sabine, Niemann Stefan
Abstract excerpt
Genotypic analysis of 103 multidrug-resistant Mycobacterium tuberculosis strains isolated in Germany in 2001 revealed that mutations in codon 531 (75.7%) of the rpoB gene and codon 315 (88.4%) of the katG gene are most frequent. Beijing genotype strains (60.2% of all isolates) displayed a different distribution of resistance mutations than non-Beijing strains.
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