Article
Comparison of drug resistance genotypes between Beijing and non-Beijing family strains of Mycobacterium tuberculosis in Korea.
Journal of microbiological methods - 1 Nov 2005
Park Young Kil, Shin Sonya, Ryu Sungweon, Cho Sang Nae, Koh Won-Jung, Kwon O Jung, Shim Young Soo, Lew Woo Jin, Bai Gill Han
Abstract excerpt
The frequency of resistance genotypes among Beijing and non-Beijing strains was compared using a reverse blot hybridization assay to detect mutations within genes associated with rifampicin (rpoB) and isoniazid (katG, inhA, and ahpC) resistance. Of the 743 Mycobacterium tuberculosis isolates, 569 (77%) belonged to Beijing family. The proportion of Beijing strains was significantly higher among MDR-TB isolates...
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