Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance levels and rpoB gene mutations among in vitro-selected rifampin-resistant Mycobacterium tuberculosis mutants.

Antimicrobial agents and chemotherapy - 1 Aug 2006

Huitric Emma, Werngren Jim, Juréen Pontus, Hoffner Sven

Abstract excerpt

The distribution and resistance levels of 189 in vitro-selected rifampin-resistant Mycobacterium tuberculosis mutants of Beijing and other genotypes were determined. Apart from a higher amount of codon 522 point mutations and large deletions, a spread of mutations similar to that reported for clinical isolates was seen. Most mutations were correlated with high-level resistance; a lower level, or a MIC of <16...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotics, Antitubercular
Share to DNA-Directed RNA Polymerases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to In Vitro Techniques

Share to Mycobacterium tuberculosis

Share to Point Mutation

Share to Rifampin

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 16870787
DOI: 10.1128/AAC.00303-06
PMCID: PMC1538691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance levels and rpoB gene mutations among in vitro-selected rifampin-resistant Mycobacterium tuberculosis mutants.PMID 16870787Read ↗

Characterization of rpoB mutations in rifampicin-resistant Mycobacterium tuberculosis isolated in China.Semantic proximity Read ↗

Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, ChinaSemantic proximity Read ↗

Rifampin resistance-associated mutations in the RIF resistance-determining region (RRDR) of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, ChinaSemantic proximity Read ↗

Mutations in the rpoB gene of multidrug-resistant Mycobacterium tuberculosis isolates from China.Semantic proximity Read ↗

Rifampin-resistance-associated mutations in the rifampin-resistance-determining region of the rpoB gene of Mycobacterium tuberculosis clinical isolates in Shanghai, PR China.Semantic proximity Read ↗

Characterization of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis from eastern China.Semantic proximity Read ↗

Mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains isolated in Brazil and France.Semantic proximity Read ↗

Characterization of Mutations Conferring Resistance to Rifampin in Mycobacterium tuberculosis Clinical Strains.Semantic proximity Read ↗

Evaluation of the frequency of mutation genes in multidrug-resistant tuberculosis (MDR-TB) strains in Beijing, China.Semantic proximity Read ↗

rpoB gene mutation profile in rifampicin-resistant Mycobacterium tuberculosis clinical isolates from Guizhou, one of the highest incidence rate regions in ChinaSemantic proximity Read ↗

[Characterization of rpoB mutation in rifampin - resistant clinical Mycobacterium tuberculosis isolates from China].Semantic proximity Read ↗

Characterization of a 411-bp fragment of the rpoB gene in clinical isolates of Mycobacterium tuberculosis in a university hospital in northern Taiwan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.