Article
Acquired PTPN11 mutations occur rarely in adult patients with myelodysplastic syndromes and chronic myelomonocytic leukemia.
Leukemia research - 1 Apr 2005
Loh Mignon L, Martinelli Simone, Cordeddu Viviana, Reynolds Melissa G, Vattikuti Shashaank, Lee Connie M, Wulfert Michael, Germing Ulrich, Haas Peter, Niemeyer Charlotte, Beran Miloslav E, Strom Sara, Lübbert Michael, Sorcini Mariella, Estey Elihu H, Gattermann Norbert, Tartaglia Marco
Abstract excerpt
Myelodysplastic syndromes (MDS) are comprised of a heterogeneous group of stem cell disorders characterized by ineffective hematopoiesis and susceptibility to transform to acute myeloid leukemia. The molecular pathways underlying disease initiation and evolution are still largely unknown. We rece...
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