Article
De novo childhood myelodysplastic/myeloproliferative disease with unique molecular characteristics.
British journal of haematology - 1 Jul 2012
Ismael Olfat, Shimada Akira, Hama Asahito, Elshazley Momen, Muramatsu Hideki, Goto Aya, Sakaguchi Hirotoshi, Tanaka Makito, Takahashi Yoshiyuki, Yinyan Xu, Fukuda Minoru, Miyajima Yuji, Yamashita Yuka, Horibe Keizo, Hanada Ryoji, Ito Masafumi, Kojima Seiji
Abstract excerpt
Myelodysplastic/myeloproliferative uclassifiable (MDS/MPN-U) is a rare myeloid neoplasm characterized by myelodysplasia and myeloproliferation at the time of initial presentation, which is usually a diagnosis of exclusion. The molecular pathogenesis of MDS/MPN-U patients remains to be elucidated. Among five patients diagnosed with MDS/MPN-U, three patients harboured RUNX1 (AML1) mutations; one carried somatic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.