Article
Mapping and verification of susceptibility loci for smoking quantity using permutation linkage analysis.
The pharmacogenomics journal - 1 Jan 2005
Wang D, Ma J Z, Li M D
Abstract excerpt
Nicotine dependence is the most prevalent form of drug addiction in the US and throughout the world. Epidemiological studies demonstrate that genetics accounts for at least 50% of the liability to nicotine dependence. However, there have been very limited linkage studies providing convincing evidence of susceptibility genomic loci for this disorder. In this study, we conducted genome-wide permutation linkage...
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