Article
Haplotype effects on human survival: logistic regression models applied to unphased genotype data.
Annals of human genetics - 1 Mar 2005
Tan Q, Christiansen L, Bathum L, Zhao J H, Vach W, Vaupel J W, Christensen K, Kruse T A
Abstract excerpt
Haplotype based linkage disequilibrium (LD) mapping exhibits higher power than the single locus approach because it makes use of the LD information contained in the flanking markers. New statistical methods have been proposed to help to infer haplotype effects on human diseases using multi-locus genotype data collected from unrelated individuals. In this paper, we introduce a statistical procedure for measuring...
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