Article
How genes influence life span: the biodemography of human survival.
Rejuvenation research - 1 Aug 2012
Yashin Anatoliy I, Wu Deqing, Arbeev Konstantin G, Stallard Eric, Land Kenneth C, Ukraintseva Svetlana V
Abstract excerpt
BACKGROUND: In genome-wide association studies (GWAS) of human life span, none of the genetic variants has reached the level of genome-wide statistical significance. The roles of such variants in life span regulation remain unclear. DATA AND METHOD: A biodemographic analyses was done of genetic regulation of life span using data on low-significance longevity alleles selected in the earlier GWAS of the original...
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