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Article

Expression of toll-like receptor 4 and endotoxin responsiveness in mice during perinatal period.

Pediatric research - 1 May 2005

Harju Kirsi, Ojaniemi Marja, Rounioja Samuli, Glumoff Virpi, Paananen Reija, Vuolteenaho Reetta, Hallman Mikko

Abstract excerpt

Endotoxin [lipopolysaccharide (LPS)] from Gram-negative bacteria is found in amniotic fluid in intrauterine infections that associate with the risk for spontaneous premature birth, bronchopulmonary dysplasia (BPD), and respiratory distress syndrome. Toll-like receptor 4 (TLR4) is the signaling receptor for LPS. The aim was to investigate the primary inflammatory response in mice shortly after administration of...

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Source

Identifiers

PMID: 15718365
DOI: 10.1203/01.PDR.0000156212.03459.A9

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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