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Article

The enhancer I core region contributes to the replication level of hepatitis B virus in vivo and in vitro.

Journal of virology - 1 Mar 2000

Bock C T, Malek N P, Tillmann H L, Manns M P, Trautwein C

Abstract excerpt

Chronic hepatitis B virus (HBV) infection can lead to liver cirrhosis and hepatocellular carcinoma. Long-term interaction of the immune system with the virus results in the selection of escape mutants and viral persistence. In this work we characterize mutations in the enhancer I region isolated prior to liver transplantation from the HBV genomes of 10 patients with chronic HBV infection. The HBV-genomes were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

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Source

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Identifiers

PMID: 10666249
DOI: 10.1128/jvi.74.5.2193-2202.2000
PMCID: PMC111700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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