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Effects of Preanalytical Factors on the Molecular Size of Cell-Free DNA in Blood

12 Feb 2005

Abstract excerpt

Recently, plasma DNA analysis has been increasingly explored for different clinical diagnostic purposes. Previous studies have shown that the concentration of plasma DNA is increased in patients with neoplastic diseases (1), pregnancy-related complications (2)(3), trauma(4), and certain autoimmune diseases (5). In addition to quantitative analysis, qualitative changes in plasma DNA have also been investigated in...

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PMID: 15708950
DOI: 10.1373/clinchem.2004.046219

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