Article
Plasma cfDNA analysis can be facilitated by membrane based filtration of whole blood regardless of additive
2023-07-07
Abstract excerpt
Cell-free DNA (cfDNA) has emerged as a pivotal biomarker for various noninvasive screening applications such as noninvasive prenatal screening, minimum residual disease monitoring, and transplant rejection prediction. However, the efficacy of these applications is heavily reliant on the detection of minority nucleic acid species amidst a vast background of host DNA. Therefore, it is crucial to prevent the dilution...
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Identifiers and source
- Literature Corpus work
- 354d945f-89ef-5e20-983b-73dc8471cc15
- DOI
- 10.1101/2023.07.05.23292260