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Article

Human astrovirus C-terminal nsP1a protein is involved in RNA replication.

Virology - 1 Mar 2005

Guix Susana, Caballero Santiago, Bosch Albert, Pintó Rosa M

Abstract excerpt

Human astrovirus nonstructural C-terminal nsP1a protein, which contains a hypervariable region (HVR) and colocalizes with the endoplasmic reticulum and viral RNA, has been suggested to be involved in the RNA replication process. Four viruses differing only in their C-terminal nsP1a protein, corresponding to HVR-derived genotypes IV, V, VI, and XII, were all able to replicate in CaCo-2 cells but displayed...

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Source

Identifiers

PMID: 15708598
DOI: 10.1016/j.virol.2004.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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