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The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranes

2024-01-09

Abstract excerpt

An essential aspect of viral replication is the anchoring of the replication complex (RC) to cellular membranes. Positive-sense RNA viruses employ diverse strategies, including co-translational membrane targeting through signal peptides and co-opting cellular membrane trafficking components. Often, N-terminal nonstructural proteins play a crucial role in linking the RC to membranes, facilitating the early associat...

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Literature Corpus work
68ab0535-de8f-5815-ba5c-dabaa17ffc68
DOI
10.1101/2024.01.09.574783
Open publication

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The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranesDOI 10.1101/2024.01.09.574783
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