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Article

Genetic analysis of the hypervariable region of the human astrovirus nsP1a coding region: design of a new RFLP typing method.

Journal of medical virology - 1 Feb 2008

Guix Susana, Caballero Santiago, Fuentes Cristina, Bosch Albert, Pintó Rosa M

Abstract excerpt

Human astroviruses (HAstV) are causative agents of viral gastroenteritis worldwide. A hypervariable region (HVR) is located close to the C-terminus of the nsP1a, and recent data support the involvement of the HVR-containing nonstructural protein in viral RNA replication processes, suggesting a correlation between variability in this region and pathogenic properties. The HVR of the C-terminal nsP1a coding region...

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PMID: 18098163
DOI: 10.1002/jmv.21058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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