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Propagation of Astrovirus VA1, a Neurotropic Human Astrovirus, in Cell Culture

13 Jul 2017

Abstract excerpt

ABSTRACT Astrovirus VA1/HMO-C (VA1; mamastrovirus 9) is a recently discovered astrovirus genotype that is divergent from the classic human astroviruses (mamastrovirus 1). The gastrointestinal tract is presumed to be the primary site of infection and pathogenicity for astroviruses. However, VA1 has been independently detected in brain tissue of five cases of human encephalitis. Studies of the pathogenicity of VA1...

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PMID: 28701405
DOI: 10.1128/jvi.00740-17

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