Article
Transcriptional changes underlying the secretory activation phase of mammary gland development.
Molecular endocrinology (Baltimore, Md.) - 1 Jul 2005
Naylor Matthew J, Oakes Samantha R, Gardiner-Garden Margaret, Harris Jessica, Blazek Katrina, Ho Timothy W C, Li Foo C, Wynick David, Walker Ameae M, Ormandy Christopher J
Abstract excerpt
The secretory activation stage of mammary gland development occurs after parturition and converts inactive lobuloalveoli to active milk secretion. This process is triggered by progestin withdrawal and depends upon augmented prolactin (Prl) signaling. Little is known about the Prl-induced transcriptional changes that occur in the mammary gland to drive this process. To examine changes in the mammary transcriptome...
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