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Article

Developmental transition of brown adipose tissue from a thermogenic to a lipogenic phenotype in neonatal goats revealed by single-nucleus transcriptomics.

Zoological research - 18 May 2026

Zhao Le, Zhu Qing-Jun, Li Min-Hao, Yang Hai-Li, Zhao Yong-Ju

Abstract excerpt

Brown adipose tissue (BAT) is essential for neonatal thermogenesis and early-life metabolic adaptation. In goat neonates, BAT is primarily concentrated in the perirenal region and rapidly regresses during the first month after birth, yet the cellular and molecular programs driving this transition remain poorly defined. In the present study, a comprehensive single-nucleus transcriptomic atlas of perirenal adipose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42237940
DOI: 10.24272/j.issn.2095-8137.2025.236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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