Article
Selectivity of ertapenem for Pseudomonas aeruginosa mutants cross-resistant to other carbapenems.
The Journal of antimicrobial chemotherapy - 1 Mar 2005
Livermore David M, Mushtaq Shazad, Warner Marina
Abstract excerpt
OBJECTIVES: Ertapenem and other carbapenems will be used increasingly, as extended-spectrum beta-lactamases become more prevalent even among community-acquired pathogens. There is, however, concern that this use will select for resistances to imipenem and meropenem in nosocomial pathogens, notably Pseudomonas aeruginosa, and we investigated the validity of this concern. METHODS: Single-step selection experiments...
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