Article
Pharmacodynamic activity of ertapenem versus multidrug-resistant genotypically characterized extended-spectrum beta-lactamase-producing Escherichia coli using an in vitro model.
The Journal of antimicrobial chemotherapy - 1 Mar 2008
Zhanel George G, Baudry Patricia, Vashisht Vibhu, Laing Nancy, Noreddin Ayman M, Hoban Daryl J
Abstract excerpt
BACKGROUND: This study assessed the pharmacodynamic activity of ertapenem against multidrug-resistant (MDR) genotypically characterized extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli using an in vitro model. METHODS: Six ESBL-producing E. coli with the CTX-M-15 genotype were studied. All six strains were MDR (defined as resistance to third-generation cephalosporins and > or = two other...
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