Article
A role of STAT3 in Rho GTPase-regulated cell migration and proliferation.
The Journal of biological chemistry - 29 Apr 2005
Debidda Marcella, Wang Lei, Zang Heesuk, Poli Valeria, Zheng Yi
Abstract excerpt
Rho family GTPases and STAT3 act as mediators of cytokine and growth factor signaling in a variety of cellular functions involved in inflammation, tumorigenesis, and development. In the course of searching for their functional connections, we found by using STAT3 knock-out mouse embryonic fibroblasts that RhoA, Rac1, and Cdc42 could cause nonspecific activation of STAT3 promoter-driven luciferase reporter in the...
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