Article
[Investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar].
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery - 1 Jan 2005
Wang Chun-mei, Hiko Hyakusoku, Nakazawa Nando
Abstract excerpt
OBJECTIVE: To investigate the codon-72 polymorphism of the tumor suppressor gene p53, codon-72 encodes arginine (Arg) or proline (Pro) for a genetic predisposition,to keloid or hypertrophic scar. METHODS: The distribution of codon 72 polymorphism of p53 gene was analyzed from the 54 keloid and 30 hypertrophic scar(HS)of the Japanese patients with restriction fragment length polymorphism analysis and DNA sequence...
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