Article
[p53 gene codon 72 polymorphism and susceptibility to keloid].
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery - 1 May 2005
Zhuo Yang, Gao Jian-hua, Luo Shen-qiu, Zeng Wei-sen, Hu Zhi-qi, Lu Feng, Zhao Yong-zhong
Abstract excerpt
OBJECTIVE: To investigate the relationship between p53 codon 72 polymorphism and susceptibility to keloid in a southern Chinese population. METHODS: The p53 genotypes were determined by polymerase chain reaction-reverse dot blot (PCR-RDB) and DNA direct sequencing in 45 patients with keloid and 60 unrelated healthy controls. RESULTS: The frequency of the p53 Pro allele among keloid patients was significantly...
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