Article
Comparison of two screening methods for in-house genotyping in clinical pharmacology units.
International journal of clinical pharmacology and therapeutics - 1 Jan 2005
Darimont J, Grösch S, Skarke C, Geisslinger G, Lötsch J
Abstract excerpt
Two genetic screening methods, the fluorescence resonance energy transfer (FRET) technique on the LightCycler and the real-time pyrophosphate detection technique on the Pyrosequencer have been compared with regard to their usefulness as screening methods for subject recruitment in clinical studies in pharmacology units. Two SNPs of possible clinical relevance were selected, namely the 118A>G SNP of the OPRM1 gene...
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