Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Polymorphism of ABCB1 and ABCG2 genes encoding drug transporters and their investigation by pyrosequencing].

Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2012

Dribnokhodova O P, Mironov K O, Dunaeva E A, Shipulin G A

Abstract excerpt

Published data on the effect of transporter propeins of the ABC family in the features of drug pharmacokinetics in the human organism are reviewed. Clinical significance of mononucleotide polymorphisms in ABCB1 and ABCG2 genes is analyzed. A set of genetic tests based on pyrosequencing for determing the allele state in rs1128503 (1236 T > C), rs2032582 (2677T > A/G), rs1045642 (3435 T > A/C), rs2231142 (421C >...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to ATP-Binding Cassette Transporters
Share to Neoplasm Proteins
Share to Pharmacogenetics
Share to Polymorphism, Single Nucleotide
Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 23240156

Genes

ABCB1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Polymorphism of ABCB1 and ABCG2 genes encoding drug transporters and their investigation by pyrosequencing].PMID 23240156Read ↗

Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature.Semantic proximity Read ↗

Single nucleotide polymorphisms in ABCC2 and ABCB1 genes and their clinical impact in physiology and drug response.Semantic proximity Read ↗

Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease.Semantic proximity Read ↗

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.Semantic proximity Read ↗

Functional Significance of Genetic Polymorphisms in P-glycoprotein (MDR1, ABCB1) and Breast Cancer Resistance Protein (BCRP, ABCG2)Semantic proximity Read ↗

[Pharmacogenetics of anti-cancer drugs].Semantic proximity Read ↗

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.Semantic proximity Read ↗

[Genetic polymorphisms of human ABC transporter ABCG2: Porphyria risk and ER quality control].Semantic proximity Read ↗

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2Semantic proximity Read ↗

[Functional SNPs of the breast cancer resistance protein (ABCG2) gene altering the pharmacokinetics/pharmacodynamics of anticancer agents].Semantic proximity Read ↗

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.Semantic proximity Read ↗

[ABC transporters' impact on effect and metabolism of drugs].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.