A genomic region evolving toward different GC contents in humans and chimpanzees indicates a recent and regionally limited shift in the mutation pattern.

doi:10.1093/molbev/msi109

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Article

A genomic region evolving toward different GC contents in humans and chimpanzees indicates a recent and regionally limited shift in the mutation pattern.

Molecular biology and evolution - 1 May 2005

Ebersberger Ingo, Meyer Matthias

Abstract excerpt

DNA sequences evolving differently in the human and chimpanzee genomes signal recent and regionally limited changes in the process of DNA sequence evolution. Here we present the comparison of 90 kb from the nonrecombining part of the human Y chromosome to the corresponding part of the chimpanzee genome using gorilla as out-group. Our results reveal a significant difference in the region-specific substitution...

Topics

Animals
Biological Clocks
DNA, Intergenic
Evolution, Molecular
GC Rich Sequence
Genetic Variation
Genome
Hominidae
Humans
Mutation
Pan troglodytes
Phylogeny

Source

Open in PubMed

Identifiers

PMID: 15703238
DOI: 10.1093/molbev/msi109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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