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Article

Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: enlarging genus Homo.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2003

Wildman Derek E, Uddin Monica, Liu Guozhen, Grossman Lawrence I, Goodman Morris

Abstract excerpt

What do functionally important DNA sites, those scrutinized and shaped by natural selection, tell us about the place of humans in evolution? Here we compare approximately 90 kb of coding DNA nucleotide sequence from 97 human genes to their sequenced chimpanzee counterparts and to available sequenced gorilla, orangutan, and Old World monkey counterparts, and, on a more limited basis, to mouse. The nonsynonymous...

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Identifiers

PMID: 12766228
DOI: 10.1073/pnas.1232172100
PMCID: PMC165850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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