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Article

Mutational biosynthesis--a tool for the generation of structural diversity in the biosynthesis of antibiotics.

Applied microbiology and biotechnology - 1 Aug 2005

Weist S, Süssmuth R D

Abstract excerpt

Natural products represent an important source of drugs in a number of therapeutic fields, e.g. antiinfectives and cancer therapy. Natural products are considered as biologically validated lead structures, and evolution of compounds with novel or enhanced biological properties is expected from the generation of structural diversity in natural product libraries. However, natural products are often structurally...

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PMID: 15702315
DOI: 10.1007/s00253-005-1891-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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